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Making cough syrup with Magnetic Coupled Mixers

Published on Jan 21, 2021 10:45:26 AM


The highest percentage of the Sterimixer installed base is in the biopharma industry but, biopharma is just a segment of the global pharmaceutical industry. There are numerous applications in traditional pharmaceutical processes that can benefit from the advantages that magnetic coupled mixers offer.


A contract manufacturer had been making a wide variety of cough syrups using top entry mixers. The business was steadily increasing and four new tanks were being added but, instead of doing things the same old way, they were looking for a way to make their process more hygienic. One of the steps that were identified as a candidate for upgrading was the mixing process.

How that led to a bottom-mounted Magnetic Mixer

The primary benefit of the Sterimixer is containment and isolation – everything inside stays in and everything outside stays out. Another important benefit is the ability to do mixing to the last drop – mix small batches or premixes in large tanks. Sterimixers have traditionally been associated with waterlike mixing applications but, cough syrups are clearly not waterlike. Depending on the recipe, they may be several hundred centipoises before adding in an appropriate safety factor. How much of a safety factor is appropriate?

Traditional pharmaceutical customers have some of the same concerns about product integrity that biopharma customers have. Steridose has the products to address these concerns during the mixing steps.

Finding the right mixer

Contract manufacturers need flexibility. They may be making a 200 centipoise cough syrup today and they may get a contract for a 500 centipoise cough syrup tomorrow. The specific gravity will also vary with the recipe. Steridose’s engineers used the data provided by the customer to arrive at a mixer selection that provides the customer with a reasonable amount of mixing in reserve, should they ever need it. The Steridose Selection Tool & Information Resource (STIR) sizing program is available here for everyone to use.

For more information about Liquid Mixing and Agitation Equipment please visit our mixing technology page.

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Posted by Matt Baumber
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Topics: Sterimixer, Magnetic Coupled Mixer